Prognosis of Spindle Cell Sarcoma

Cancers start when a one or more normal cells start to proliferate abnormally. From this time, there will be a formation of tumor. It will start small and will grow larger and larger.

Where Do Cancer Cells Come From?

There are still lots of studies to be made in order to know why cancer cells are formed. But, there are already theories about it. Some researchers said that it is due to mutation, while some doesn’t believe this theory.

In the mutation theory of cancer cells, it is stated that a normal cell is transformed into a cancer cell due to genetic damage. The oncogenes, which promotes mitotic division and the tumor suppressor genes, which inhibits mitotic division, are damaged. It means that these two genes are altered. It may be that the oncogenes are turned on while the tumor suppressor genes are turned off.

On the other hand, a researcher observed that when there is injury or inflammation, healer spindle cells are present and proliferate in the site to heal the wound. He said that when a single spindle cell doesn’t stop healing and continues to multiply, it will form a tumor, specifically a spindle cell sarcoma tumor. Hence, that single healer cell is a cancer cell.

Diagnosing Spindle Cell Sarcoma

Spindle cell sarcoma diagnosis is the same to some common cancers. There are lots of methods that are used in order to diagnose a certain cancer. Not all cancers are diagnosed with the same method because of the sensitivity of other anatomical structures in the body. The types of diagnosing cancers are genetic testing, punch biopsy, laboratory testing, imaging, fine needle aspiration, tumor biopsy, surgical diagnosis and endoscopic examination.

For spindle cell sarcoma diagnosis, the most common sampling techniques are the fine needle aspiration, surgery and punch biopsy. Doctors may require only one, but it is better to have more tests to be sure about the results.

Treatment and Prognosis of Spindle Cell Sarcoma

Spindle cell sarcoma prognosis may be good or poor, depending on the grade and stage of the cancer. Spindle cell sarcoma is almost usually low-grade, which is the slow mitotic rate grade. However, it progresses from stage 1 and up depending on its invasiveness.

If the cancer is just in stage 1, the prognosis is good. The best chosen treatment is wide surgical removal of the lesion. However, if it is not possible, chemotherapy, radiation therapy and other treatment procedures are suggested.

The grimness of the spindle cell sarcoma prognosis starts if it is already in stage 2 or up. At this stage, it is already in medium to high grade and it may have already invaded the adjacent structures. What is worst is when it is near to a very sensitive visceral organ. This may be the lungs or the heart.

When it is on this stage, complete surgical removal is not possible since it may include adjacent vital structures. That is why the only possible treatments are radiation therapy and chemotherapy. However, it is still risky because it may still damage the vital tissues adjacent to the tumor. If the tumor is treated, the next problem is that adjacent structures may start to fail and not function efficiently.