Spindle Cell Sarcoma of the Prostate

The prostate is a type of exocrine gland that is present in the male reproductive system of most mammals. Its anatomic, physiologic and chemical features differ diversely among species. The general function of the prostate gland is to produce a milky white alkaline fluid that comprises 50% to 75% of the semen volume together with it are the seminal vesicle fluid and the spermatozoa.

How Do Cancers Begin?

Normally, the cells in your body divide or undergo mitosis in a regular manner. In a normal mitosis, there are cells that will die and there are new cells that will be formed. As you grow older, there will be formation of new cells that will replace the dying ones, which is why your body is getting bigger. However, this happens in a regular pattern.

Cancer starts when cells begin to divide abnormally. Even a single abnormal cell or cancer cell can form a very large tumor because of its rapid abnormal growth. Cancer cells are formed because of damage to DNA due to exposure to harmful chemicals, pollution or radiation.

What is Sarcoma?

Sarcoma is a kind of cancer which is derived from certain body tissues such as muscle or bone. The two major kinds of sarcoma are soft tissue sarcoma and bone sarcoma.

Prostatic Spindle Cell Sarcoma

The spindle cell sarcoma prostate type is a type of sarcoma that arises from the prostate gland (as the name implies). It is composed of spindle-shaped cells that come from mutated cells of the prostate.

Smooth muscle cell is an example of cell with spindle-like appearance. It is a type of muscle cell that has involuntary action. It performs its function efficiently without your will. It lines the walls of your visceral organs such as the GI tract, uterus, and prostate. This cell is also found in the walls of the blood vessels. Since blood vessels are distributed throughout your body, spindle cell sarcomas can start anywhere.

Types of Prostatic Spindle Cell Sarcoma

There are various spindle cell sarcoma prostate types depending on the specific origin of the tumor in the prostate. These are the:

  • Stromal tumors of uncertain malignant potential or STUMP
  • Sarcomatoid carcinoma or carcinosarcoma
  • Stromal sarcoma

Signs and Symptoms

The signs and symptoms of spindle cell sarcoma of the prostate may also be due to other factors. However, if you have these symptoms, it is best to have a checkup with your general practitioner to be sure about your condition.

Patients with spindle cell sarcoma of prostate experiences:

  • Pain in the symphysis pubis
  • Acute retention of urine
  • Scalding micturization or releasing only a few droplets of urine accompanied with burning pain
  • Enlarged prostate
  • Firm, rubbery and tender prostate


Since sarcoma of the prostate may include acute retention of urine, catheterization may be advised. The major treatments for the cancer are as follows:

  • Surgical removal of the tumor
  • Cryosurgery or cryotherapy
  • Hormone therapy
  • Radiation therapy to prevent recurrence of the cancer
  • Chemotherapy to prevent the recurrence of the cancer and as well as to treat cancer which already spread