All About Spindle Cell Sarcoma Types

Tumors are formed when there is rapid proliferation of mutated abnormal cells or most commonly known as cancer cells. These are cells which have DNA damage, specifically in the oncogenes and the tumor suppressor genes. These genes are responsible in controlling the mitotic rate of the cells.


Sarcoma is a cancer of connective tissue, which is derived from mesenchymal cells. Therefore, this type of cancer may come from fat, bone, muscle, cartilage, hematopoietic or vascular tissues.

This type of sarcoma is a cancer of connective tissue, which is composed of spindle-shaped cellular material. There are various spindle-shaped cells that are found in the body. Smooth muscle tissue has a spindle-shape appearance and they form the walls of your blood vessels as well as some of the organs such as the GI tract. Another kind is the healer cells, which also possess the spindle like appearance.

Since this type of cancer resembles spindle cells, researchers believe that they may arise from the smooth muscle cells or the healer spindle cells. They said that genetic factors may also cause a person to have this condition, but even though you don’t have any cancer promoting genes, you may still develop a cancer.

Whenever you have an injury in your body, healer spindle cells will always be present in the area to heal the damage. Researchers said that if a single spindle cell doesn’t die after the healing process and it continues to multiply, it will form a tumor. This is already a cancer cell, they said.

However, they still don’t know why some of the healer cells remain and continue to multiply. They just notice that it actually happens to some cancer patients. However, there is another research suggesting that the inability of the pancreas to secrete pancreatic enzymes after the healing process is the reason why they remain. These pancreatic enzymes digest the excess healer spindle cell material.


There are various types depending on the location. Since spindle cell tissue are usually found throughout the body, there are many types and they can be found on your:

  • Tongue
  • Uterus
  • Lung
  • Pancreas
  • Prostate
  • Liver
  • Heart
  • Stomach
  • Kidneys
  • Breast
  • Abdomen
  • Nose
  • Eye
  • Brain
  • Muscles

As you can see, this type of cancer can affect many different areas of the human body. Among these ares of the body, the most common is the mother’s womb, the uterus. The organ is rich in smooth muscle tissue and blood supply. This may be the reason why it is common in the uterus. However, it is still a rare kind of cancer.

Unlike other cancers, some researchers believe that they are in between benign and malignant tissues. It is because they can invade adjacent structures like malignant cellular material, but they do not usually undergo metastasis, which is the primary feature of malignant tissue, which benign tumors can’t do.

If you have this cancer anywhere on your body and it metastasizes, the most common secondary sites are the liver, lungs and the kidneys. This is because the vascular supply in these organs is very rich and they are almost connected everywhere in the body.